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1

Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments

Karen Blackburn, Donald Bjerke, George Daston, Susan Felter, Catherine Mahony, Jorge Naciff, Steven Robison, Shengde Wu

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 414 KB

english, 2011

2

Differential expression of annexins I-VI in the rat dorsal root ganglia and spinal cord

Naciff, Jorge M., Kaetzel, Marcia A., Behbehani, Michael M., Dedman, John R.

Journal:

The Journal of Comparative Neurology

Year:

1996

Language:

english

File:

PDF, 5.72 MB

english, 1996

3

Evaluation of the gene expression changes induced by 17-α-ethynyl estradiol in the immature uterus/ovaries of the rat using high density oligonucleotide arrays

Jorge M. Naciff, Suzanne M. Torontali, Gary I. Overmann, Gregory J. Carr, Jay P. Tiesman, George P. Daston

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2005

Language:

english

File:

PDF, 235 KB

english, 2005

4

Predicting developmental toxicity through toxicogenomics

George P. Daston, Jorge M. Naciff

Journal:

Birth Defects Research Part C: Embryo Today: Reviews

Year:

2010

Language:

english

File:

PDF, 165 KB

english, 2010

5

The genomic response of Ishikawa cells to bisphenol A exposure is dose- and time-dependent

Jorge M. Naciff, Zubin S. Khambatta, Timothy D. Reichling, Gregory J. Carr, Jay P. Tiesman, David W. Singleton, Sohaib A. Khan, George P. Daston

Journal:

Year:

2010

Language:

english

File:

PDF, 295 KB

english, 2010

6

Identification and Transgenic Analysis of a Murine Promoter that Targets Cholinergic Neuron Expression

Jorge M. Naciff, Michael M. Behbehani, Hidemi Misawa, John R. Dedman

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 700 KB

english, 1999

7

Targeted neutralization of calcineurin, by expression of an inhibitor peptide under the control of a cholinergic specific promoter in PC12 cells, promotes neurite outgrowth in the presence of NGF

Jorge M. Naciff, Karen L. King, John R. Dedman

Journal:

Metabolic Brain Disease

Year:

2000

Language:

english

File:

PDF, 1.52 MB

english, 2000

8

Targeted Neutralization of Calcineurin, by Expression of an Inhibitor Peptide Under the Control of a Cholinergic Specific Promoter in PC12 Cells, Promotes Neurite Outgrowth in the Presence of NGF

Jorge M. Naciff, Karen L. King, John R. Dedman

Journal:

Metabolic Brain Disease

Year:

2000

File:

PDF, 1.68 MB

2000

9

Effects of Transplacental 17-α-Ethynyl Estradiol or Bisphenol A on the Developmental Profile of Steroidogenic Acute Regulatory Protein in the Rat Testis

Karla A. Horstman, Jorge M. Naciff, Gary J. Overmann, Leslie M. Foertsch, Brian D. Richardson, George P. Daston

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 997 KB

english, 2012

10

Gene expression changes related to growth and differentiation in the fetal and juvenile reproductive system of the female rat: evaluation of microarray results

George P. Daston, Jorge M. Naciff

Journal:

Reproductive Toxicology

Year:

2005

Language:

english

File:

PDF, 257 KB

english, 2005

11

Framework for Identifying Chemicals with Structural Features Associated with the Potential to Act as Developmental or Reproductive Toxicants

Wu, Shengde, Fisher, Joan, Naciff, Jorge, Laufersweiler, Michael, Lester, Cathy, Daston, George, Blackburn, Karen

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 3.96 MB

english, 2013

12

Design of a Microsphere-Based High-Throughput Gene Expression Assay to Determine Estrogenic Potential

Jorge M. Naciff, Brian D. Richardson, Kerry G. Oliver, M. Lynn Jump, Suzanne M. Torontali, Kenton D. Juhlin, Gregory J. Carr, Jennifer R. Paine, Jay P. Tiesman and George P. Daston

Journal:

Environmental Health Perspectives

Year:

2005

Language:

english

File:

PDF, 3.10 MB

english, 2005

13

Toxicogenomics || Overview of the Application of Transcription Profiling Using Selected Nephrotoxicants for Toxicology Assessment

Jeffrey A. Kramer, Syril D. Pettit, Rupesh P. Amin, Timothy A. Bertram, Bruce Car, Michael Cunningham, Sandra W. Curtiss, John W. Davis, Clive Kind, Michael Lawton, Jorge M. Naciff, Victor Oreffo, Ric

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 1.12 MB

english, 2004

14

Toxicogenomics || Identification of Platform-Independent Gene Expression Markers of Cisplatin Nephrotoxicity

Karol L. Thompson, Cynthia A. Afshari, Rupesh P. Amin, Timothy A. Bertram, Bruce Car, Michael Cunningham, Clive Kind, Jeffrey A. Kramer, Michael Lawton, Michael Mirsky, Jorge M. Naciff, Victor Oreffo,

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 1.92 MB

english, 2004

15

A novel transcriptomics based in vitro method to compare and predict hepatotoxicity based on mode of action

De Abrew, K. Nadira, Overmann, Gary J., Adams, Rachel L., Tiesman, Jay P., Dunavent, John, Shan, Yuqing K., Carr, Gregory J., Daston, George P., Naciff, Jorge M.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.53 MB

english, 2015

16

Toxicogenomic Approach to Endocrine Disrupters: Identification of a Transcript Profile Characteristic of Chemicals with Estrogenic Activity

Naciff, Jorge M., Daston, George P.

Journal:

Toxicologic Pathology

Year:

2004

Language:

english

File:

PDF, 5.13 MB

english, 2004

17

A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity

Blackburn, Karen, Daston, George, Fisher, Joan, Lester, Cathy, Naciff, Jorge M., Rufer, Echoleah S., Stuard, Sharon B., Woeller, Kara

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

18

Design of a Microsphere-Based High-Throughput Gene Expression Assay to Determine Estrogenic Potential

Naciff, Jorge M., Richardson, Brian D., Oliver, Kerry G., Jump, M. Lynn, Torontali, Suzanne M., Juhlin, Kenton D., Carr, Gregory J., Paine, Jennifer R., Tiesman, Jay P., Daston, George P.

Journal:

Environmental Health Perspectives

Year:

2005

Language:

english

File:

PDF, 4.39 MB

english, 2005

19

Impact of the Phytoestrogen Content of Laboratory Animal Feed on the Gene Expression Profile of the Reproductive System in the Immature Female Rat

Jorge M. Naciff, Gary J. Overmann, Suzanne M. Torontali, Gregory J. Carr, Jay P. Tiesman and George P. Daston

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 2.23 MB

english, 2004

20

Dose- and Time-Dependent Transcriptional Response of Ishikawa Cells Exposed to Genistein.

Naciff, Jorge M., Khambatta, Zubin S., Carr, Gregory J., Tiesman, Jay P., Singleton, David W., Khan, Sohaib A., Daston, George P.

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 506 KB

english, 2016

21

Grouping Thirty Four Chemicals Based on Mode of Action Using Connectivity Mapping

De Abrew, K. Nadira, Kainkaryam, Raghunandan M., Shan, Yuqing K., Overmann, Gary J., Settivari, Raja S., Wang, Xiaohong, Xu, Jun, Adams, Rachel L., Tiesman, Jay P., Carney, Edward W., Naciff, Jorge M.

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 1.96 MB

english, 2016

22

Molecular characterization of the mouse vesicular acetylcholine transporter gene

Naciff, Jorge M., Misawa, Hidemi, Dedman, John R.

Journal:

Year:

1997

Language:

english

File:

PDF, 191 KB

english, 1997

23

In Response : Ecotoxicogenomics addressing future needs: An industry perspective

Versteeg, Donald J., Naciff, Jorge M.

Journal:

Environmental Toxicology and Chemistry

Year:

2015

Language:

english

File:

PDF, 92 KB

english, 2015

24

In Vitro Toxicology || The Use of Transcriptional Profiling in In Vitro Systems to Determine the Potential Estrogenic Activity of Chemicals of Interest

Naciff, Jorge M.

Year:

2018

Language:

english

File:

PDF, 679 KB

english, 2018

25

Impact of the Phytoestrogen Content of Laboratory Animal Feed on the Gene Expression Profile of the Reproductive System in the Immature Female Rat

Naciff, Jorge M., Overmann, Gary J., Torontali, Suzanne M., Carr, Gregory J., Tiesman, Jay P., Daston, George P.

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 580 KB

english, 2004

26

Identification of platform-independent gene expression markers of cisplatin nephrotoxicity.

Thompson, Karol L, Afshari, Cynthia A, Amin, Rupesh P, Bertram, Timothy A, Car, Bruce, Cunningham, Michael, Kind, Clive, Kramer, Jeffrey A, Lawton, Michael, Mirsky, Michael, Naciff, Jorge M, Oreffo, V

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 237 KB

english, 2004

27

Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment.

Kramer, Jeffrey A, Pettit, Syril D, Amin, Rupesh P, Bertram, Timothy A, Car, Bruce, Cunningham, Michael, Curtiss, Sandra W, Davis, John W, Kind, Clive, Lawton, Michael, Naciff, Jorge M, Oreffo, Victor

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 119 KB

english, 2004

28

Use of Connectivity Mapping to Support Read Across: A Deeper Dive Using Data from 186 Chemicals, 19 Cell lines and 2 Case Studies

De Abrew, K. Nadira, Shan, Yuqing K., Wang, Xiaohong, Krailler, Jesse M., Kainkaryam, Raghunandan M., Lester, Cathy C., Settivari, Raja S., LeBaron, Matthew J., Naciff, Jorge M., Daston, George P.

Journal:

Year:

2019

Language:

english

File:

PDF, 848 KB

english, 2019

29

Use of Connectivity Mapping to Support Read Across: A Deeper Dive Using Data from 186 Chemicals, 19 Cell lines and 2 Case Studies

De Abrew, K. Nadira, Shan, Yuqing K., Wang, Xiaohong, Krailler, Jesse M., Kainkaryam, Raghunandan M., Lester, Cathy C., Settivari, Raja S., LeBaron, Matthew J., Naciff, Jorge M., Daston, George P.

Journal:

Year:

2019

File:

PDF, 848 KB

2019

30

Incorporation of in vitro techniques for botanicals dietary supplement safety assessment â Towards evaluation of developmental and reproductive toxicity (DART)

VanderMolen, Karen M., Naciff, Jorge M., Kennedy, Kevin, Otto-Bruc, Annie, Shan, Yuqing, Wang, Xiaohong, Daston, George P., Mahony, Catherine

Journal:

Food and Chemical Toxicology

Year:

2020

File:

PDF, 3.79 MB

2020